There is one month to go until the start of the 2025/2026 Serie A season: while the big teams are aiming for the Scudetto, at the bottom of the table a tough battle is brewing to avoid relegation. In this article, we analyze the teams most at risk according to the antepost odds of the leading bookmakers.
The new Serie A season is upon us and, as every year, in addition to the race for the Scudetto, the fight to avoid relegation is just as important. The bookmakers’ antepost odds offer a first look at the teams that, on paper, are most at risk. The rules are clear: the bottom three teams will be relegated to Serie B at the end of the 2025/2026 season. But that’s not all: even those who narrowly escaped relegation the previous year are back at the starting blocks with the label of ‘team at risk’.
According to the bookmakers, the main candidates for relegation this season are Cremonese, Pisa, and Verona, closely followed by Lecce.
In the following paragraphs, we will analyze these teams, looking at their form, transfer market activity, and motivation, to understand who could be facing the drop to Serie B.
Two years on, Cremonese are back in Serie A after an exciting playoff final in Serie B, won against Spezia with a 3-2 aggregate score. The Lombardy-based team, led by Giovanni Stroppa, managed to come back and win promotion by leveraging solid play and an underdog mentality. Despite the euphoria surrounding their return to the top flight, bookmakers show little confidence in the club’s survival: relegation is priced at 1.83 on bet365 and 1.50 on Sisal. To date, it is among the lowest odds of the teams in contention, a sign that analysts are concerned about the solidity of the current squad and its ability to cope with the pace of Serie A.
Cremonese relegation – listed at 1.83 on bet365, 1.50 on Sisal
Serie A relegation odds: Pisa also among the teams in the balance

For Pisa, newly promoted to Serie A after a 34-year absence, the challenge to stay up will be anything but easy. The Tuscan club dominated Serie B in 2024/2025 under the guidance of Pippo Inzaghi, who recently handed over the reins to Alberto Gilardino. Among the protagonists of the promotion was Matteo Tramoni, Pisa’s top scorer with 14 goals and three assists in 26 appearances, a decisive talent in the club’s journey to the top flight.
Despite their recent success, bookmakers consider Pisa one of the most vulnerable teams: relegation is priced at 2.00 on bet365, a sign of little confidence in the squad’s ability to hold its own and adapt to Serie A. To hope for survival, targeted signings and immediate improvement in terms of consistency and mentality will be needed.
Pisa relegation – odds of 2.00 on bet365, 1.57 on Sisal
Verona among the candidates for Serie B: relegation is priced at 2.38

Hellas Verona secured its place in Serie A for the 2024/25 season, finishing 14th thanks to a thrilling comeback on the final day that condemned Empoli and Venezia to relegation. It was a heart-stopping finale that rewarded the determination of the Scaligeri, who were able to turn around a delicate situation in the final weeks of the championship.
Despite this, bookmakers are skeptical about the new 2025/26 season: Verona’s relegation is priced at 2.38 on bet365 and 2.50 on Sisal. This is a clear indication that, even with a certain degree of technical continuity, analysts still consider the squad too fragile, especially in the absence of targeted reinforcements to withstand the impact of an entire season in the top flight.
Relegation odds: Lecce

Lecce had a complicated season in 2024/25, remaining embroiled in the relegation battle until the last round. Only a crucial 1-0 win away to Lazio, played with a man down for most of the second half, prevented them from returning to Serie B. Their place in the top flight is assured for this year, but let’s see how Lecce will fare. Despite the confidence they have gained, bookmakers remain cautious: Lecce’s relegation odds are set at 2.62 on bet365 and 2.75 on Sisal. This means that the risk is real, especially considering the need to increase experience and quality in order to better face the new tournament.